Life Extension ComfortMAX

{"id":645306482733,"title":"Life Extension ComfortMAX","handle":"life-extension-comfortmax","description":"\u003cp\u003eComfortMAX™ is a unique supplement that promotes nerve health and comfort. By inhibiting inflammatory compounds in your nerve cells and encouraging healthy neurotransmitter levels in your brain, ComfortMAX™ helps to reduce discomfort. Take one convenient tablet in the morning and one at night. Live comfortably with ComfortMAX™!\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cu\u003eBenefits at a Glance: \u003c\/u\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eComfortMAX™ provides dual-action nerve support to help inhibit discomfort\u003c\/li\u003e\n\u003cli\u003ePEA inhibits inflammatory factors to help calm excited nerves\u003c\/li\u003e\n\u003cli\u003eHonokiol extract supports GABA neurotransmitters affected by discomfort\u003c\/li\u003e\n\u003cli\u003eThese combined actions help you stay comfortable throughout the day\u003c\/li\u003e\n\u003cli\u003eMorning and nighttime dosing for around-the-clock support\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eComfortMAX™ delivers two potent ingredients: palmitoylethanolamide or PEA and honokiol, a compound derived from Magnolia bark. By promoting nerve comfort in two separate yet complementary ways, the ingredients in ComfortMAX™ represent a revolutionary step in helping to relieve discomfort.\u003csup\u003e1,2\u003c\/sup\u003e Try ComfortMAX™ today!\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMore facts about ComfortMAX™\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAccording to the National Institutes of Health, nearly 25 million Americans experience daily discomfort.\u003csup\u003e3\u003c\/sup\u003e This kind of discomfort can affect mood, mobility, and quality of life.\u003csup\u003e4\u003c\/sup\u003e The reasons for physical discomfort vary, but the way we experience that discomfort doesn't: Our peripheral nerves are responsible for delivering sensory information (an itch, temperature change, physical pressure, etc.) to the brain. And that's where ComfortMAX™ comes in.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePalmitoylethanolamide (PEA)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePalmitoylethanolamide (or PEA) is a unique kind of fatty acid. Your body naturally produces PEA as part of a healthy inflammatory and immune response.\u003csup\u003e5\u003c\/sup\u003e In fact, PEA inhibits the secretion of inflammatory compounds from mast cells, a type of white blood cell. As we age, our number of mast cells decrease, causing our remaining mast cells to work harder. That can make them overly sensitive, activating inflammatory processes linked to nerve discomfort. By inhibiting inflammatory compounds released by mast cells,\u003csup\u003e6-8\u003c\/sup\u003e PEA promotes your body's natural response to uncomfortable nerve stimuli at the cellular level.\u003csup\u003e9\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003eIn a randomized controlled trial following 636 patients over a period of three weeks, 600 mg of PEA every day profoundly affected scores that measured relative comfort and quality of life.\u003csup\u003e10\u003c\/sup\u003e In a smaller randomized controlled trial, patients reported that PEA outperformed standard care for discomfort when taken for two weeks.\u003csup\u003e11\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHonokiol \u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eHonokiol is a naturally occurring lignan compound derived from several species of magnolia, several of which have been used in traditional Asian medicine for centuries.\u003csup\u003e12,13\u003c\/sup\u003e Now, scientists are discovering that honokiol has applications for nerve health and comfort.\u003c\/p\u003e\n\u003cp\u003eHonokiol has been shown to support the \"calming\" GABA receptors in the brain,\u003csup\u003e14,15\u003c\/sup\u003e which affects the way the brain perceives discomfort.\u003csup\u003e16\u003c\/sup\u003e Furthermore, honokiol is quickly taken up into the brain in animal models,\u003csup\u003e17-19\u003c\/sup\u003e making it an ideal ingredient for nerve health and comfort.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eUnique Daytime \u0026amp; Nighttime Formula\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eComfortMAX™ has been formulated to be taken twice a day, one tablet in the morning and one tablet at night right before bed, for day and night help with relieving discomfort. Each package of ComfortMAX™ provides a 30 day supply. Try ComfortMAX™ today!\u003c\/p\u003e\n\u003cp\u003eReferences\u003c\/p\u003e\n\u003cdiv class=\"collapse in\" aria-expanded=\"true\"\u003e\u003c\/div\u003e\n\u003cdiv class=\"collapse in\" aria-expanded=\"true\"\u003e\u003c\/div\u003e\n\u003cdiv class=\"collapse in\" id=\"prodRefCollapse\" aria-expanded=\"true\"\u003e\n\u003cdiv class=\"ref-content\"\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cem\u003eJournal of natural products\u003c\/em\u003e. 1998;61(1):135-138.\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003ePain physician\u003c\/em\u003e. 2016;19(2):11-24.\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003ejournal of pain: official journal of the American Pain Society\u003c\/em\u003e. 2015;16(8):769-780.\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003eJournal of pain research\u003c\/em\u003e. 2016;9:457-467.\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003eCNS \u0026amp; neurological disorders drug targets\u003c\/em\u003e. 2013;12(1):78-83.\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003eEuropean journal of pharmacology\u003c\/em\u003e. 1996;300(3):227-236.\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003eBrain Behav Immun\u003c\/em\u003e. 2011;25(6):1099-1112.\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003eCNS \u0026amp; neurological disorders drug targets\u003c\/em\u003e. 2013;12(1):34-44.\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003ein Neurosciences\u003c\/em\u003e. 1996;19(11):514-520.\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003eDolor. Investigación Clínica \u0026amp; Terapéutica\u003c\/em\u003e. Vol 252010:35-42.\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003eJournal of orofacial pain\u003c\/em\u003e. 2012;26(2):99-104.\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003eThe Journal of pharmacy and pharmacology\u003c\/em\u003e. 1998;50(7):819-826.\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003eThe Journal of pharmacy and pharmacology\u003c\/em\u003e. 2000;52(11):1425-1429.\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003eNeuropharmacology\u003c\/em\u003e. 2012;62(8):2507-2514.\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003eNeurochemical research\u003c\/em\u003e. 1999;24(12):1593-1602.\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003eScience (New York, NY)\u003c\/em\u003e. 2000;288(5472):1765-1768.\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003ePloS one\u003c\/em\u003e. 2011;6(4):e18490.\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003eEuropean journal of drug metabolism and pharmacokinetics\u003c\/em\u003e. 2016;41(5):587-594.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch5\u003eSuggested Use\u003c\/h5\u003e\n\u003cp\u003eTake one (1) AM tablet in the morning and one (1) PM tablet before bed, with or without food, or as recommended by a healthcare practitioner.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","published_at":"2018-06-20T14:01:58-07:00","created_at":"2018-06-20T14:06:54-07:00","vendor":"Life Extension","type":"Muscle Aches \u0026 Pain","tags":["life-extension","muscle-aches-pain","nerve-support","online","regular","useposinv"],"price":3300,"price_min":3300,"price_max":3300,"available":true,"price_varies":false,"compare_at_price":null,"compare_at_price_min":0,"compare_at_price_max":0,"compare_at_price_varies":false,"variants":[{"id":39647869272198,"title":"30\/30 AM\/PM Vegetarian Tablets","option1":"30\/30 AM\/PM Vegetarian Tablets","option2":null,"option3":null,"sku":"10432","requires_shipping":true,"taxable":true,"featured_image":{"id":33890915844230,"product_id":645306482733,"position":1,"created_at":"2024-09-07T13:28:10-07:00","updated_at":"2024-09-07T13:28:10-07:00","alt":"Life Extension ComfortMAX-30\/30 AM\/PM Vegetarian Tablets-N101 Nutrition","width":400,"height":400,"src":"\/\/www.n101nutrition.com\/cdn\/shop\/files\/n101-nutrition-life-extension-comfortmax-3030-ampm-vegetarian-tablets.jpg?v=1725740890","variant_ids":[39647869272198]},"available":true,"name":"Life Extension ComfortMAX - 30\/30 AM\/PM Vegetarian Tablets","public_title":"30\/30 AM\/PM Vegetarian Tablets","options":["30\/30 AM\/PM Vegetarian Tablets"],"price":3300,"weight":118,"compare_at_price":null,"inventory_quantity":2,"inventory_management":"shopify","inventory_policy":"deny","barcode":"737870220268","featured_media":{"alt":"Life Extension ComfortMAX-30\/30 AM\/PM Vegetarian Tablets-N101 Nutrition","id":26812217229446,"position":1,"preview_image":{"aspect_ratio":1.0,"height":400,"width":400,"src":"\/\/www.n101nutrition.com\/cdn\/shop\/files\/n101-nutrition-life-extension-comfortmax-3030-ampm-vegetarian-tablets.jpg?v=1725740890"}},"requires_selling_plan":false,"selling_plan_allocations":[]}],"images":["\/\/www.n101nutrition.com\/cdn\/shop\/files\/n101-nutrition-life-extension-comfortmax-3030-ampm-vegetarian-tablets.jpg?v=1725740890","\/\/www.n101nutrition.com\/cdn\/shop\/files\/n101-nutrition-life-extension-comfortmax-3030-ampm-vegetarian-tablets-2.jpg?v=1725740894"],"featured_image":"\/\/www.n101nutrition.com\/cdn\/shop\/files\/n101-nutrition-life-extension-comfortmax-3030-ampm-vegetarian-tablets.jpg?v=1725740890","options":["Size"],"media":[{"alt":"Life Extension ComfortMAX-30\/30 AM\/PM Vegetarian Tablets-N101 Nutrition","id":26812217229446,"position":1,"preview_image":{"aspect_ratio":1.0,"height":400,"width":400,"src":"\/\/www.n101nutrition.com\/cdn\/shop\/files\/n101-nutrition-life-extension-comfortmax-3030-ampm-vegetarian-tablets.jpg?v=1725740890"},"aspect_ratio":1.0,"height":400,"media_type":"image","src":"\/\/www.n101nutrition.com\/cdn\/shop\/files\/n101-nutrition-life-extension-comfortmax-3030-ampm-vegetarian-tablets.jpg?v=1725740890","width":400},{"alt":"Life Extension ComfortMAX-30\/30 AM\/PM Vegetarian Tablets-N101 Nutrition","id":26812217262214,"position":2,"preview_image":{"aspect_ratio":1.0,"height":400,"width":400,"src":"\/\/www.n101nutrition.com\/cdn\/shop\/files\/n101-nutrition-life-extension-comfortmax-3030-ampm-vegetarian-tablets-2.jpg?v=1725740894"},"aspect_ratio":1.0,"height":400,"media_type":"image","src":"\/\/www.n101nutrition.com\/cdn\/shop\/files\/n101-nutrition-life-extension-comfortmax-3030-ampm-vegetarian-tablets-2.jpg?v=1725740894","width":400}],"requires_selling_plan":false,"selling_plan_groups":[],"content":"\u003cp\u003eComfortMAX™ is a unique supplement that promotes nerve health and comfort. By inhibiting inflammatory compounds in your nerve cells and encouraging healthy neurotransmitter levels in your brain, ComfortMAX™ helps to reduce discomfort. Take one convenient tablet in the morning and one at night. Live comfortably with ComfortMAX™!\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cu\u003eBenefits at a Glance: \u003c\/u\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eComfortMAX™ provides dual-action nerve support to help inhibit discomfort\u003c\/li\u003e\n\u003cli\u003ePEA inhibits inflammatory factors to help calm excited nerves\u003c\/li\u003e\n\u003cli\u003eHonokiol extract supports GABA neurotransmitters affected by discomfort\u003c\/li\u003e\n\u003cli\u003eThese combined actions help you stay comfortable throughout the day\u003c\/li\u003e\n\u003cli\u003eMorning and nighttime dosing for around-the-clock support\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eComfortMAX™ delivers two potent ingredients: palmitoylethanolamide or PEA and honokiol, a compound derived from Magnolia bark. By promoting nerve comfort in two separate yet complementary ways, the ingredients in ComfortMAX™ represent a revolutionary step in helping to relieve discomfort.\u003csup\u003e1,2\u003c\/sup\u003e Try ComfortMAX™ today!\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMore facts about ComfortMAX™\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAccording to the National Institutes of Health, nearly 25 million Americans experience daily discomfort.\u003csup\u003e3\u003c\/sup\u003e This kind of discomfort can affect mood, mobility, and quality of life.\u003csup\u003e4\u003c\/sup\u003e The reasons for physical discomfort vary, but the way we experience that discomfort doesn't: Our peripheral nerves are responsible for delivering sensory information (an itch, temperature change, physical pressure, etc.) to the brain. And that's where ComfortMAX™ comes in.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePalmitoylethanolamide (PEA)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePalmitoylethanolamide (or PEA) is a unique kind of fatty acid. Your body naturally produces PEA as part of a healthy inflammatory and immune response.\u003csup\u003e5\u003c\/sup\u003e In fact, PEA inhibits the secretion of inflammatory compounds from mast cells, a type of white blood cell. As we age, our number of mast cells decrease, causing our remaining mast cells to work harder. That can make them overly sensitive, activating inflammatory processes linked to nerve discomfort. By inhibiting inflammatory compounds released by mast cells,\u003csup\u003e6-8\u003c\/sup\u003e PEA promotes your body's natural response to uncomfortable nerve stimuli at the cellular level.\u003csup\u003e9\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003eIn a randomized controlled trial following 636 patients over a period of three weeks, 600 mg of PEA every day profoundly affected scores that measured relative comfort and quality of life.\u003csup\u003e10\u003c\/sup\u003e In a smaller randomized controlled trial, patients reported that PEA outperformed standard care for discomfort when taken for two weeks.\u003csup\u003e11\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHonokiol \u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eHonokiol is a naturally occurring lignan compound derived from several species of magnolia, several of which have been used in traditional Asian medicine for centuries.\u003csup\u003e12,13\u003c\/sup\u003e Now, scientists are discovering that honokiol has applications for nerve health and comfort.\u003c\/p\u003e\n\u003cp\u003eHonokiol has been shown to support the \"calming\" GABA receptors in the brain,\u003csup\u003e14,15\u003c\/sup\u003e which affects the way the brain perceives discomfort.\u003csup\u003e16\u003c\/sup\u003e Furthermore, honokiol is quickly taken up into the brain in animal models,\u003csup\u003e17-19\u003c\/sup\u003e making it an ideal ingredient for nerve health and comfort.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eUnique Daytime \u0026amp; Nighttime Formula\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eComfortMAX™ has been formulated to be taken twice a day, one tablet in the morning and one tablet at night right before bed, for day and night help with relieving discomfort. Each package of ComfortMAX™ provides a 30 day supply. Try ComfortMAX™ today!\u003c\/p\u003e\n\u003cp\u003eReferences\u003c\/p\u003e\n\u003cdiv class=\"collapse in\" aria-expanded=\"true\"\u003e\u003c\/div\u003e\n\u003cdiv class=\"collapse in\" aria-expanded=\"true\"\u003e\u003c\/div\u003e\n\u003cdiv class=\"collapse in\" id=\"prodRefCollapse\" aria-expanded=\"true\"\u003e\n\u003cdiv class=\"ref-content\"\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cem\u003eJournal of natural products\u003c\/em\u003e. 1998;61(1):135-138.\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003ePain physician\u003c\/em\u003e. 2016;19(2):11-24.\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003ejournal of pain: official journal of the American Pain Society\u003c\/em\u003e. 2015;16(8):769-780.\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003eJournal of pain research\u003c\/em\u003e. 2016;9:457-467.\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003eCNS \u0026amp; neurological disorders drug targets\u003c\/em\u003e. 2013;12(1):78-83.\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003eEuropean journal of pharmacology\u003c\/em\u003e. 1996;300(3):227-236.\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003eBrain Behav Immun\u003c\/em\u003e. 2011;25(6):1099-1112.\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003eCNS \u0026amp; neurological disorders drug targets\u003c\/em\u003e. 2013;12(1):34-44.\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003ein Neurosciences\u003c\/em\u003e. 1996;19(11):514-520.\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003eDolor. Investigación Clínica \u0026amp; Terapéutica\u003c\/em\u003e. Vol 252010:35-42.\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003eJournal of orofacial pain\u003c\/em\u003e. 2012;26(2):99-104.\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003eThe Journal of pharmacy and pharmacology\u003c\/em\u003e. 1998;50(7):819-826.\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003eThe Journal of pharmacy and pharmacology\u003c\/em\u003e. 2000;52(11):1425-1429.\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003eNeuropharmacology\u003c\/em\u003e. 2012;62(8):2507-2514.\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003eNeurochemical research\u003c\/em\u003e. 1999;24(12):1593-1602.\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003eScience (New York, NY)\u003c\/em\u003e. 2000;288(5472):1765-1768.\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003ePloS one\u003c\/em\u003e. 2011;6(4):e18490.\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003eEuropean journal of drug metabolism and pharmacokinetics\u003c\/em\u003e. 2016;41(5):587-594.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch5\u003eSuggested Use\u003c\/h5\u003e\n\u003cp\u003eTake one (1) AM tablet in the morning and one (1) PM tablet before bed, with or without food, or as recommended by a healthcare practitioner.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e"}